What is a Biological Age Test or Body Clock Test?

Most people are fully aware of how old they are in a chronological sense, since they know precisely how long they have been alive for. However, there is an important distinction to be made between your chronological age and your biological age or body clock age. Your biological age is much harder to calculate, as it is not a measurement of the length of time you have been alive for, but rather a fundamental measurement of how physically ‘aged’ your body is. Ever wondered why some people appear to be much younger or much older than their actual chronological age? The answer is very simple, it is because they have the body of someone who is much younger or older than they normally would at their current age. They themselves have physically aged faster or slower than average, and hence they appear to have physical and mental characteristics which are at odds with their chronomical age. A biological aging test is designed to determine your current biological age, by comparing physiological characteristics of your body to the average population in order to determine how quickly you are aging.

Why is biological age so important?

Biological age is a direct indicator of your general health, as well as being the most powerful tool to date for predicting overall lifespan. What is even more important to realize is that your biological age and the rate at which your biological age changes over time is in no way fixed, and can actively change depending on how you treat your body. There is undoubtedly a large genetic component at play, but there are numerous lifestyle factors which play a significant role in how quickly you age. Smoking, excessive drinking, drug abuse, a sedentary lifestyle, obesity, and poor diets have all been shown to significantly increase the rate at which individuals age. By extension, positive lifestyle changes such as losing weight, exercising, and decreasing personal levels of stress have been shown to help slow the biological aging process. If your biological age is higher than your chronological age, this would indicate that you are aging at an accelerated rate, which in turn means that you are likely to have both a shorter life expectancy and be more likely to suffer from age related diseases. Biological age testing can help you to identify the rate at which you are aging, and in turn allow you to make the necessary lifestyle changes to slow your rate of aging. Even if your biological age is less than your chronological age, further testing can always be utilized to further improve your rate of aging in order to maximize your health and longevity.

What types of Biological Aging tests are available?

There have been many different forms of biological aging tests throughout the years, however today there are two main ways in which biological age is measured.

The first of these tests is known as an Epigenetic Age Test, which is commonly referred to as an Epigenetic Clock test, or GrimAge testing. By far the most accurate form of this test is called the Horvath Clock developed by Dr Steve Horvath, which is commonly considered to be the most accurate form of biological age testing currently available, and has been proven to be the most accurate predictor to life expectancy currently developed. The Horvath Clock works by measuring age related changes in your DNA sequences, specifically measuring the rate at which your DNA is modified through the addition and subtraction of methyl groups to your chromosomes  as you get older. Horvath Clock testing requires nothing more than a small sample (0.5ml) of capillary blood, which can be collected either in a clinical or via a home testing kit.

The Second commonly used form of biological age testing is known as PhenoAge Test. Instead of examining an individual’s DNA, PhenoAge testing measures common age-related biomarkers, which is known to change during aging. PhenoAge testing involves a simple blood test which examines nine common age related biomarkers (Albumin, ALP, Creatinine, Blood Glucose, CRP, Lymphocyte percentage, White Blood Cell Count, Mean Corpuscular Volume, and Red Cell Distribution Width). Collectively these results can then be used to calculate your biological age. Although this form of testing is less accurate when compared to epigenetic testing, PhenoAge testing is still regarded as a valuable indicator of biological age, and is often used alongside epigenetic biological age testing in medical research.

Read the Research

Nature article in Biological Ageing Reversal

Nature article in Biological Ageing Reversa

Biological Age and Life Expectancy

Biological age directly relates to life expectancy, since it is a direct measurement of how quickly you are aging. Epigenetic aging tests can not only be used to determine your biological age, but by extrapolating this data it is possible to accurately predict a person’s life expectancy based upon their current epigenetic biological age. GrimAge testing ( Grimage_Patient_Brochure IHC) is the most accurate form of life expectancy testing currently available, and is functionally identical to the standard Horvath clock with regards to how the actual test is administered. It is important to remember that a GrimAge prediction is not a definitive answer to what your lifespan will be, but rather a highly accurate prediction of your life expectancy based upon your current health and lifestyle. Just as the rate of biological aging is malleable and can be improved with intervention, GrimAge life expectancy can also be increased.

Can Biological Age Predict Illness and Mortality?

Biological age, just like chronological age, is not used as a diagnostic tool for any one single illness or disease. However, biological age has been shown to directly predict all forms of mortality, as well as being linked directly to many illnesses, such as certain types of cancer, cardiovascular disease, and dementia. Since many diseases have contributing factors other than age, it has proven difficult to directly correlate general biological age to specific illnesses, however the strong correlation to life expectancy indicates that biological age is directly linked to age-related illnesses.

How Can Biological Age Testing Help Me?

Biological age or body clock testing are powerful tools for monitoring how your body is changing over time. Although it is not yet possible to reverse the aging process, it is currently believed that slowing the aging process is certainly possible, even with our current limited understanding of the process. Accelerated aging is not necessarily obvious for appearance alone, and many individuals may be suffering from premature aging without realizing it. Biological age testing offers individuals the chance to assess how exactly they are aging on a biological level, which can not only be useful for both assessing their current overall health, but also help them decrease the rate at which they are aging through lifestyle changes, dietary supplements, or even medical interventions.

How to Reduce Your Biological Age

Reducing your biological age, which refers to how old your body seems compared to your chronological age, involves a combination of lifestyle changes, medical interventions, and potentially some cutting-edge research. Here are some evidence-based strategies to consider:

 1.Dietary Habits:•Balanced Diet: Consume a diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats.•Caloric Restriction: Some studies suggest that reduced calorie intake without malnutrition can extend lifespan and delay age-related diseases.•Intermittent Fasting: This has been associated with improved cellular health and metabolic functions.

2.Physical Activity:•Engage in regular aerobic exercise, strength training, and flexibility exercises. This can improve cardiovascular health, muscle mass, bone density, and reduce the risk of many age-related diseases.

3.Stress Management:•Chronic stress has been linked to accelerated cellular aging. Techniques such as meditation, deep breathing, and mindfulness can help manage stress.4.Sleep:•Aim for 7-9 hours of quality sleep each night. Sleep is crucial for cellular repair and cognitive function.5.Avoid Smoking and Limit Alcohol:•Both can accelerate aging and increase the risk of various diseases.

6.Regular Health Check-ups:•Stay up-to-date with recommended screenings and medical check-ups to catch and address potential health issues early.

7.Supplementation:•Some supplements, such as resveratrol, CoQ10, and omega-3 fatty acids, have been researched for their potential anti-aging benefits. Always consult with a healthcare provider before starting any supplementation.

8.Maintain Social Connections:•Strong social ties have been linked to increased longevity and better mental well-being.

9.Mental Stimulation:•Engage in activities that challenge the brain, like puzzles, reading, or learning a new skill.

10.Avoid Excessive Sun Exposure:•Sun damage can accelerate skin aging. Use sun protection and avoid prolonged exposure.

11.Medical Interventions:•Hormone replacement therapy, certain medications, and other treatments are being researched for their potential to slow the aging process. However, the risks and benefits should be thoroughly discussed with a medical professional.

12. Stay Updated with Research: • There are continuous advancements in the field of anti-aging and regenerative medicine. While many treatments are experimental, staying informed can help you make educated decisions about potential interventions.

Our Biological Age Body Clock Tests

Purchase your test online or by phone on 0345 230 3386.  If you book online, we’ll call you to schedule your pre-test consultation at a time convenient to you. Patients or guardians must be over 18 to give consent and book testing.

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