Homocysteine (Fasting) fasting blood test (Purple Top Vacutainer) to measure fasting plasma homocysteine. High levels are sometimes due to a double copy of the MTHFR gene and is associated with an increased risk of clotting, DVT, pulmonary embolism and recurrent miscarriage and pregnancy loss. Treatment fir pregnant women is with aspirin, heparin and high dose folic acid (5mg) and other supplements as below.
Treatment for high homocysteine levels will vary depending on the underlying cause. If it is due to a vitamin deficiency, dietary changes or supplements can help decrease the levels.
The following nutrients may help to lower homocysteine levels:
- betaine – trimethylglycine (TMG)
- folic acid – vitamin B9 5mg daily
- riboflavin – vitamin B2
- pyridoxine – vitamin B6 50mg daily
- cobalamin – vitamin B12
People with certain genetic differences or homocystinuria may need to take supplements and also follow a diet that limits protein throughout their lives.
Because researchers are still learning about the link between homocysteine and diseases, it is generally a good idea to take steps to keep levels within a typical range and to look after heart health by:
- eating a balanced and heart-healthy diet
- quitting smoking
- reducing alcohol consumption