Horizon Carrier Genetic Screening Test
A blood test to identify carriers of autosomal recessive genetic conditions such as Cystic Fibrosis, Fragile-X, Spinal Muscular Atrophy, Duchenne Muscular Dystrophy. If both parents are carriers of a recessive gene there is a 1 in 4 chance of having affected offspring.
Understanding what the Natera Horizon Carrier Screening Test is and how it works can help determine whether it is appropriate for you and your partner.
Everyone has two copies of 23 chromosomes — one set from your mother and one from your father for a total of 46. However, sometimes these genes can be abnormal. If you have one normal chromosome and a mutated counterpart, you are considered a “carrier.” If two carriers with the same mutation have a baby, they may pass on a genetic disorder. These types of disorders are called recessive conditions. A carrier screening panel can reveal if you and/or your partner are carriers of the same recessive disease traits.
The Horizon Test checks for up to 274 recessive and X-linked conditions that you could unknowingly pass on to a baby.
The Horizon Test offers:
- complimentary pre-and post-test genetic information and counselling
- next-generation sequencing—the latest technology—to provide better detection rates
- patient-friendly reports, fact sheets, and videos to help you understand your results
- a choice of 3 carrier screening panels (see below)
Horizon 4 Panel (Cystic Fibrosis, Fragile-X, Spinal Muscular Atrophy, Duchenne Muscular Dystrophy)
Horizon 106 Panel (comprehensive screen suitable for patients with Ashkenazi and Sephardic ancestry)
Horizon 274 Panel (pan-ethnic extended panel)