Thrombophilia Screen (Extended inc MTHFR)
Thrombophilia Screen (Extended inc MTHFR) is a blood test (4 Blue, 2 Purple, 2 Gold Top Vacutainers) to assess inherited and acquired tendencies to thrombophilia (clotting). The screen consists of both tests for different aspects of clotting and also gene mutations which affect clotting. This may have implications for deep venous thrombosis (DVT), pulmonary embolism (PE), fertility, recurrent miscarriage, poor placental function, growth restriction and stillbirth.
The screen includes lupus anticoagulant, anticardiolipin antibodies (IgG and IgM) where high values indicate APLS (antiphospholipid antibody syndrome) , prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen, protein C, protein S, activated protein C resistance, antithrombin III activity, prothrombin mutation, factor V Leiden mutation, methatetrahhydrofolate reductase (MTHFR) mutation.