Probiotics in Pregnancy

Understanding Probiotics in Pregnancy

Understanding Probiotics in Pregnancy: A Definitive Guide

Probiotics are live microorganisms that provide health benefits when consumed in adequate amounts. During pregnancy, maintaining a healthy balance of gut bacteria is crucial for both maternal and foetal health. This comprehensive guide explores the microbiome, the role of probiotics in pregnancy, specific strains studied for their benefits, dietary sources, commercially available probiotics in the UK, and safety considerations.

Click here for a more general guide to Understanding Diet and Nutrition in Pregnancy!

Understanding the Microbiome and Probiotics

The microbiome refers to the collection of microorganisms residing in and on the human body, particularly in the gut. This ecosystem plays a vital role in digestion, immunity, and hormonal regulation. During pregnancy, the microbiome undergoes changes to meet the growing needs of the mother and baby.

Probiotics are beneficial bacteria that support and restore a healthy microbiome. These live microorganisms are found in fermented foods and dietary supplements, and specific strains have been shown to offer unique health benefits.

Benefits in Pregnancy

Research has shown that probiotics can play a significant role in supporting maternal and fetal health:

1.Digestive Health

Probiotics help alleviate common gastrointestinal issues during pregnancy, such as constipation, bloating, and diarrhoea, by improving gut motility and reducing inflammation.

2.Prevention of Gestational Diabetes Mellitus (GDM)

Certain probiotic strains enhance insulin sensitivity and reduce inflammation, lowering the risk of GDM.

•   Reference: A 2016 study by Luoto et al. found probiotics reduced GDM incidence.

3.Reduced Risk of Preeclampsia and Preterm Birth

Probiotics may lower inflammation and oxidative stress, which are associated with preeclampsia and preterm birth.

•   Reference: A meta-analysis by Lassi et al. (2022) indicated probiotics’ potential in reducing these risks.

4.Allergy Prevention in Infants

Probiotics consumed during pregnancy and breastfeeding, such as Lactobacillus rhamnosus GG, have been linked to a reduced risk of eczema and allergies in infants.

•   Reference: Kalliomäki et al. (2001) reported reduced atopic eczema in infants whose mothers consumed probiotics.

5.Enhanced Immune Function

Probiotics strengthen maternal immunity, reducing infections and enhancing overall health.

Specific Probiotics Studied in Pregnancy

1. Lactobacillus rhamnosus GG (LGG)

•   Benefits: Reduces the risk of GDM, supports gut health, and prevents allergies in infants.

•   Sources: Yoghurt, fermented milk, and probiotic supplements.

2. Lactobacillus acidophilus

•   Benefits: Reduces risk of getting bacterial vaginosis (BV), improves lactose digestion, and relieves bloating.

•   Sources: Fermented dairy products and supplements.

3. Bifidobacterium lactis

•   Benefits: Enhances immunity, improves bowel regularity, and reduces inflammation.

•   Sources: Yoghurt, kefir, and probiotic supplements.

4. Saccharomyces boulardii

•   Benefits: Helps protect against diarrhoea and improves gut health.

•   Sources: Probiotic supplements and fermented beverages like kombucha.

5. Lactobacillus reuteri

•   Benefits: Supports oral health, helps alleviate bloating, and reduces inflammatory markers.

•   Sources: Supplements and fermented foods.

Commercially Available Probiotics in the UK

Here are some popular probiotic supplements available in the UK, suitable for pregnancy:

1.Optibac Probiotics For Pregnancy

•   Contains Lactobacillus rhamnosus HN001 and Bifidobacterium lactis BB-12, researched for pregnancy benefits.

2.Bio-Kult Pregnéa

•   A multi-strain probiotic with six strains of beneficial bacteria and essential vitamins for pregnancy.

3.ProVen Probiotics Pregnancy

•   Contains friendly bacteria alongside nutrients to support gut health and immunity during pregnancy.

4.Symprove Live & Active Bacteria

•   A water-based probiotic that delivers live bacteria to the gut microbiome, enhancing digestion and gut health.

5.BioCare Pregnancy BioFlora

•   Features probiotics such as Lactobacillus salivarius and Bifidobacterium bifidum, as well as prebiotic fibres like fructooligosaccharides (FOS).

Prebiotics: Supporting Probiotic Activity

Prebiotics are non-digestible fibres that feed probiotics, enhancing their effectiveness. Common sources of prebiotics include:

•   Fruits: Bananas, apples, and berries.

•   Vegetables: Garlic, onions, leeks, and asparagus.

•   Whole Grains: Oats, barley, and wheat bran.

•   Legumes: Lentils, chickpeas, and beans.

Prebiotic-rich foods or supplements are especially useful for boosting probiotic activity and maintaining a balanced microbiome during pregnancy.

Sources of Probiotics

1.Natural Sources:

•   Fermented foods like yoghurt, kefir, sauerkraut, kimchi, and miso.

2.Supplements:

•   Capsules, powders, or tablets containing clinically studied strains. Dosages typically range from 1–10 billion CFUs per day.

Safety and Considerations

In general probiotics and prebiotics are safe in pregnancy.

1.Consultation: Always consult a healthcare provider before starting probiotics during pregnancy.

2.Product Quality: Choose products with clinically studied strains, clearly labelled CFU counts, and no unnecessary additives.

3.Potential Side Effects: Minor side effects like bloating may occur initially but typically subside as the gut adjusts.

Conclusion

Probiotics are a valuable addition to maternal nutrition during pregnancy. By supporting gut health, reducing inflammation, and enhancing immunity, probiotics offer a range of benefits for both mother and baby. Incorporating probiotics through foods or supplements—paired with prebiotics for optimal effectiveness—can help achieve a healthier pregnancy.

Always consult your healthcare provider to tailor probiotic use to your individual needs.

References

1.Kalliomäki, M., et al. (2001). Probiotics in the prevention of atopic disease: A randomised placebo-controlled trial. The Lancet, 357(9262), 1076-1079.

2.Luoto, R., et al. (2016). Impact of probiotics on gestational diabetes mellitus. Journal of Nutrition, 146(2), 223-230.

3.Lassi, Z. S., et al. (2022). Role of probiotics in preventing preterm birth: A meta-analysis. The Lancet Global Health, 10(5), e676-e686.

4.Reid, G., et al. (2013). Probiotics for vaginal health in pregnancy. Best Practice & Research Clinical Obstetrics & Gynaecology, 27(1), 27-34.

5.Cryan, J. F., et al. (2019). The gut microbiome in pregnancy: A potential role in maternal mood and behaviour. Nature Reviews Neuroscience, 20(2), 69-81.

6.Ouwehand, A. C., et al. (2002). Probiotic and other functional microbes: From markets to mechanisms. Current Opinion in Biotechnology, 13(5), 483-487.

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author avatar
Bryan Beattie Lead Consultant in Fetal Medicine
Dr Robert Bryan Beattie MB BCh BAO MD FRCOG Dr Beattie qualified in 1983 from Queen’s University Belfast and is sub-specialty trained in Fetal and Maternal Medicine. He also holds the RCOG/RCR Joint Diploma in Obstetric Ultrasound. He was a founder member of the British Maternal and Fetal Medicine Society and is an internationally recognised pregnancy expert who is regularly called upon to speak at conferences and events. Dr Beattie is the founding Chairman and Trustee of the Innermost Academy, a registered charity dedicated to improving education in pregnancy care.
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